GLP-1 is a natural hormone that helps regulate blood sugar, slow digestion, and signal fullness to the brain—all of which play a key role in managing weight and glucose levels. While GLP-1 is the hormone your body produces, GLP-1 medications are called "agonists" because they mimic and activate the same receptors—essentially extending and enhancing the effects your body would normally trigger after a meal.

Ozempic is from Novo Nordisk and FDA-approved to treat type 2 diabetes and reduce the risk of major cardiovascular events in adults with known heart disease. Technically, Ozempic is not FDA-approved for weight loss. However, doctors can prescribe it “off-label” for weight loss.

Ozempic became popular due to its strong results in lowering blood sugar, noticeable weight loss side effects, and high-profile media coverage. Its once-weekly injection schedule made it convenient, and social media buzz—especially around its off-label use for weight loss—helped turn it into a household name beyond diabetes care.

Wegovy, also a Novo Nordisk product, is FDA-approved for chronic weight management in adults with obesity or those who are overweight with at least one weight-related condition like high blood pressure or type 2 diabetes. Technically, Wegovy is not approved for the treatment of type 2 diabetes. However, since it contains the same active ingredient as Ozempic, some improvements in blood sugar may still occur.